beautypg.com

Bayer HealthCare Rapidlab 800 User Manual

Page 653

background image

Operating Principles

IĆ33

The 800 system does not report alveolar oxygen tension, but uses the pO

2

(A) value

to calculate the alveolar-arterial oxygen tension difference and the arterial-alveolar
oxygen tension ratio.

AlveolarĆArterial Oxygen Tension Difference

The alveolar-arterial oxygen tension difference, pO

2

(A–a), which is sometimes

abbreviated as A–aDO

2

, is useful as an index of gas exchange within the lungs if

the ctO

2

measurements are not available. The following equation

16,28

is used:

pO

2

(A–a)(T)

= pO

2

(A)(T) – pO

2

(a)(T)

where pO

2

(A)(T) is the temperature corrected oxygen tension of alveolar gas and

pO

2

(a)(T) is the temperature corrected oxygen tension of arterial blood.

ArterialĆAlveolar Oxygen Tension Ratio

The arterial-alveolar oxygen tension ratio, pO

2

(a/A), which is also referred to as

the a/A ratio, provides an index of oxygenation that remains relatively stable when
F

I

O

2

changes. It is useful in predicting oxygen tension in alveolar gas. The

following equation

29

is used:

pO

2

(a/A)(T) =

pO

2

(a)(T)

pO

2

(A)(T)

where pO

2

(a)(T) is the temperature corrected oxygen tension of arterial blood and

pO

2

(A)(T) is the temperature corrected oxygen tension of alveolar gas.

Respiratory Index

The respiratory index (RI) is the ratio of the alveolar-arterial blood oxygen
pressure difference to arterial pO

2

. RI, another a means of assessing the extent of

pulmonary shunting, can be used instead of the alveolar-arterial oxygen tension
difference [pO

2

(A–a)]. Because RI is a ratio and not an absolute value, it does not

present the inherent problems that are seen with the pO

2

(A–a) value. The

following equation

16

is used:

RI(T) = pO

2

(A–a)(T) / pO

2

(a)(T)

where pO

2

(A–a)(T) is the temperature corrected alveolar-arterial oxygen tension

difference and pO

2

(a)(T) is the temperature corrected oxygen tension of arterial

blood.