Metrohm 732 IC Detector - Manual (Page 166)

5.5 Validation / GLP
732 IC Detector / 733 IC Separation Center
159
5.5 Validation / GLP
The requirements of GLP (Good Laboratory Practice) include a peri-
odic check of analytical measuring instruments with regard to their re-
producibility and accuracy using Standard Operating Procedures,
SOP.
The 732 IC Detector and 733 IC Separation Center as part of the com-
plete ion chromatography system, whose most important components
also include separating column, pump and evaluation system, must be
incorporated in its comprehensive validation.
Testing of the electronic and mechanical function groups of Metrohm
instruments can and should be performed as part of a regular service
by trained personnel of the manufacturing company (see section 5.2.1).
All Metrohm instruments are equipped with start-up-test routines which
check for perfect functioning of the relevant assemblies when the in-
strument is switched on. If no error message is displayed, it may be as-
sumed the instrument is operating without faults.
The Metrohm company also supplies its instruments with an integrated
diagnostic program (see section 5.4) which, in the case of possible
malfunctions or faulty behavior, allows the user to check the functioning
of certain assemblies and localize the fault. Diagnostic programs can
also be integrated in a validation procedure.