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11 appendix, 1 solvent characteristics for normal phase columns – BUCHI PrepChrom C-700 User Manual

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BÜCHI Labortechnik AG

Appendix | 11

PrepChrom C­700

105/110

11 Appendix

11.1 Solvent characteristics for normal phase columns

Solvent

Solvent

strength S

Dipole param­

eter

Proton ac­

ceptor pa­

rameter

Proton

donor pa­

rameter

Refractive in­

dex

UV limit nm

n­Pentane

0.00

0

0

0

1.358

210

Hexane

0.00

0

0

0

1.357

210

Isooctane

0.01

0

0

0

1.404

210

Petroleum ether

0.01

0

0

0

210

Cyclohexane

0.04

0

0

0

1.427

210

Xylene

0.26

0

0.5

0

1.500

290

Diisopropyl ether

0.28

0.5

0.5

0

1.368

220

Toluene

0.29

0

0.5

0

1.496

285

Diethyl ether

0.38

2

2

0

1.353

220

Chloroform

0.40

3

0.5

3

1.443

245

Dichloromethane

0.42

5.5

0.5

0

1.424

245

Tetrahydrofuran

0.45

4

3

0

1.408

220

Acetone

0.56

5

2.5

0

1.359

330

Dioxane

0.56

4

3

0

1.422

220

Ethyl acetate

0.58

3

2

0

1.370

260

Acetonitrile

0.65

8

2.5

0

1.344

200

Propanol

0.82

2.5

4

4

1.380

210

Ethanol

0.88

4

5

5

1.361

210

Methanol

0.95

5

7.5

7.5

1.329

210

Water

large

large

large

large

1.333

190