Bio-Rad Image Lab™ Software - Manual (Page 185)

Electronic Records
User Guide | 185
Documents created in secure mode can be signed at any time. When a secure
document is signed, it is saved as read-only. Image Lab cannot overwrite the
document. You can open signed documents and sign them again. The newly signed
file is saved as a second revision, and the new signatures are captured in the
document log.
Note: Image Lab can never overwrite any signed file.
You can open secure documents in standard mode of Image Lab. Selecting Save As
from the File menu creates an unsecure file. The original file is preserved. No log is
generated for the new, unsecure document. However, an entry is added to the
original log that the file has been reverted to unsecure.
Secure Documents in SAM mode
Images saved in signal accumulation mode (SAM) follow the same rules as the main
image. The rules apply when the image is saved from within a protocol. If you create
an image from a signed protocol, all resultant images must also be signed. If you try
to save a file more than once, a warning message appears asking you to confirm the
re-save. And if you confirm this re-save and click OK, Image Lab creates a new file
with an incremental revision number.
Modifying Secure Documents
You can open and change a signed document in Image Lab. The original document
is read-only and cannot be overwritten. Saving the revisions opens the Save As
dialog box. The changes are saved into a new revision with an incremental revision
number.
Each time a secure document is modified, you must provide a reason for each
change before you can sign the document. The modifications are logged in the
document log. The new signed document takes with it the entire history of the
original document in its log.