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8 glp functions, 1 general information on glp and validation, 2 glp monitoring – Metrohm 873 Biodiesel Rancimat Manual User Manual

Page 146: Glp functions, General information on glp and validation, Glp monitoring

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4.8 GLP functions

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873 Biodiesel Rancimat

4.8

GLP functions

4.8.1

General information on GLP and validation

GLP (Good Laboratory Practice) requires, amongst other things, the peri-
odical testing of analytical measuring devices for their reproducibility and
correctness on the basis of Standard Operating Procedures (SOP).

An example of such a standard operating procedure for the 873 Biodiesel
Rancimat is available from Metrohm under the title Application Bulletin No.
278 – Validation of Metrohm Rancimats
.

The operating software for the 873 Biodiesel Rancimat contains prepared
GLP tests for temperature, conductivity and gas flow measurement. The
user can determine whether and which tests have to be carried out. In addi-
tion, the time interval between the tests and the accuracy requirements can
be specified. If the GLP function is activated, each results report receives a
comment whether the GLP tests are fulfilled. Metrohm offers a GLP test set
to carry out these tests (see Optional accessories, page 180).

Further information on the subject of QA, GLP and validation can also be
found in the brochure Quality Management with Metrohm available from
your Metrohm representative.

Electronic and mechanical functional groups in Metrohm instruments can
and should be checked as part of regular service by specialist personnel of
the manufacturing company. All Metrohm instruments are provided with
start-up test routines which check the perfect functioning of the relevant
assemblies when switching on the instrument. If no error message is dis-
played, it can be assumed that the instrument functions without fault.

The 873 Biodiesel Rancimat also contains an integrated diagnostic program
which enables the service technician to check certain assemblies if any faults
or incorrect functioning occur and localize the fault.

4.8.2

GLP monitoring

Activating/Deactivating GLP monitoring

Proceed as follows to either activate or deactivate the GLP monitoring for
the temperature, the conductivity and the gas flow:

1 Open dialog window

If several instruments are connected: In the Control window, use
the menu item View

Unit x to select the required instrument.

Click on the menu item Tools

GLP test Properties....