Heidolph Synthesis 1 - Manual (Page 56)

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Thank you for buying a HEIDOLPH product. This appliance has been designed and
tested in compliance with DIN EN ISO 61010. It features ease of handling and long
service life.
SUMMARY
SUMMARY ............................................................................................................... 56
STANDARD EQUIPMENT AND OPTIONS ............................................................. 58
GENERAL INFORMATION...................................................................................... 60
SAFETY INFORMATION ......................................................................................... 61
SET UP..................................................................................................................... 62
1.
Liquid-Phase Synthesis ................................................................................. 62
1.1 Reaction Vessels ................................................................................ 62
1.1.1 Setup................................................................................................... 62
1.1.2 Install head.......................................................................................... 63
1.1.3 Built-in rotary valve.............................................................................. 63
1.1.4 Septa................................................................................................... 64
1.1.5 Capacity of reaction vessels................................................................ 64
1.2 Locate reaction vessels in heating- and condensation block .............. 64
1.2.1 Remove and install reaction vessels ................................................... 64
1.2.2 Vacuum-/ protective gas fitting with distributor (plenum)..................... 67
1.3 Connect vacuum- / inert gas lines ....................................................... 69
1.3.1 Connect vacuum- / inert gas lines ....................................................... 69
1.3.2 3-way valve, vacuum- / inert gas (standard equipment)...................... 69
1.3.3 Valve settings, vacuum-/ inert gas ...................................................... 70
1.4 Less reaction vessels.......................................................................... 70
2. Solid-phase synthesis .................................................................................... 71
2.1 Reaction vessels ................................................................................. 71
2.1.1 Setup:.................................................................................................. 71
2.1.2 Install and disassemble head / base ................................................... 72
2.1.3 Base with built-in filter ......................................................................... 72
2.1.4 Septa.................................................................................................. 72
2.1.5 Tube fitting, head and base................................................................ 73
2.1.6 Open and close valve of reaction vessel............................................. 73
2.1.7 Capacity of reaction vessels................................................................ 74
2.2 Locate reaction vessels in heating- and condensation block .............. 74
2.2.1 Install vessels...................................................................................... 74
2.3 Connect vacuum / inert gas with vessels / plenum.............................. 75
2.4 Connect vacuum- / inert gas to plenum ports...................................... 75
2.4.1 3-way valve, vacuum-/ inert gas (standard equipment)....................... 76
2.4.2 Valve settings, vacuum- / inert gas ..................................................... 76
2.5 Connect waste cube, solid-phase synthesis........................................ 77
2.5.1 Convert waste cube for deviating number of vessels .......................... 78
2.5.2 Schematic, arrangement of waste cube tubes .................................... 79
2.6 Less reaction vessels.......................................................................... 79
3. Coolant fitting, liquid- or solid-phase synthesis .............................................. 80
3.1 Coolant connector, condensation zone ............................................... 80
3.2 Coolant fitting, conditioning zone for reactions
below room temperature...................................................................... 80
4. Multiple-Evaporator........................................................................................ 80