Metrohm 743 Rancimat - Manual (Page 150)

4.8 GLP functions ￭￭￭￭￭￭￭￭￭￭￭￭￭￭￭￭￭￭￭￭￭￭
142 ￭￭￭￭￭￭￭￭ 743 Rancimat
4.8 GLP functions
4.8.1 General information on GLP and validation
GLP (Good Laboratory Practice) requires, amongst other things, the peri-
odical testing of analytical measuring devices for their reproducibility and
correctness on the basis of Standard Operating Procedures (SOP).
An example of such a standard operating procedure for the 743 Rancimat
is available from Metrohm under the title Application Bulletin No. 278 –
Validation of Metrohm Rancimats.
The operating software for the 743 Rancimat contains prepared GLP
tests for temperature, conductivity and gas flow measurement. The user
can determine whether and which tests have to be carried out. In addi-
tion, the time interval between the tests and the accuracy requirements
can be specified. If the GLP function is activated, each results report
receives a comment whether the GLP tests are fulfilled. Metrohm offers a
GLP test set to carry out these tests (see Optional accessories, page 185).
Further information on the subject of QA, GLP and validation can also be
found in the brochure Quality Management with Metrohm available from
your Metrohm representative.
Electronic and mechanical functional groups in Metrohm instruments can
and should be checked as part of regular service by specialist personnel of
the manufacturing company. All Metrohm instruments are provided with
start-up test routines which check the perfect functioning of the relevant
assemblies when switching on the instrument. If no error message is dis-
played, it can be assumed that the instrument functions without fault.
The 743 Rancimat also contains an integrated diagnostic program which
enables the service technician to check certain assemblies if any faults or
incorrect functioning occur and localize the fault.
4.8.2 GLP monitoring
Activating/Deactivating GLP monitoring
Proceed as follows to either activate or deactivate the GLP monitoring for
the temperature, the conductivity and the gas flow:
1 Open dialog window
￭ If several instruments are connected: In the Control window,
use the menu item View
▶ Unit x to select the required instru-
ment.
￭ Click on the menu item Tools ▶ GLP test ▶ Properties....