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Waters AccellPlus QMA and CM Bulk Media User Manual

Care and use manual, Waters accellplus qma and cm bulk media

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Waters AccellPlus QMA and CM Bulk Media

1

[ Care and Use ManUal ]

I. calculatIng bulk medIa needs

II. packed column use

a. Slurry Column Packing

b. Dry Column Packing

c. Column Equilibration
d. Packed Column Testing

III. bulk medIa use

IV. addItIonal InformatIon

a. Chemical Compatibility

b. Sanitization
c. Regeneration
d. Short-Term Storage (less than 72 hours)
e. Long-Term Storage (more than 72 hours)
f. Troubleshooting

Waters AccellPlus QMA and CM Bulk Media

Waters AccellPlus

QMA anion exchange and Waters AccellPlus CM

cation exchange packing materials are polymer-coated, silica-based
media of 37-55 µm particles with a 300Å pore size. AccellPlus
media is prepared by a patented copolymerization process that
encapsulates the rigid silica base with a hydrophilic bonding layer
and a highly stable cross-linked functional layer. AccellPlus media
provides excellent recovery and high resolution of bio-molecules. The
rigid and non-compressible structure of AccellPlus media makes it
well suited for the purification and isolation of proteins, enzymes and
immunoglobulins, particularly when preparative or process scale-up is
intended.

AccellPlus ion exchange media is available in 100 gm and 500 gm
bottles (Table 1). Larger quantities are available on request. The
media is shipped as a dry white finely divided powder and can be
stored dry.

Table 1. AccellPlus Ion-Exchange Bulk Packings

Particle

Description

Particle

Size

Pore
Size

Qty.

Part No.

AccellPlus QMA

40

µm

300Å

100 g

WAT010742

Anion Exchanger

40

µm

300Å

500 g

WAT010741

AccellPlus CM

40

µm

300Å

100 g

WAT010740

Cation Exchanger

40

µm

300Å

500 g

WAT010739