Drucker Diagnostics Paralens Advance User Manual
Page 49
7.4.1 Precision (continued)
In a separate precision study, intra- and inter-run
precision were assessed using a dual level QBC
Control (#424304). The controls were assayed on
multiple days at three sites using QBC AccuTubes
and the QBC Autoread Plus System. The results of
this study are presented in Table 7-2.
7-3
Table 7-2
.
AccuTube Precision Using QBC Control
Normal Level
Abnormal Level
Parameter
Site
Mean Value
Intra-run
Inter-run
Mean Value
Intra-run
Inter-run
% CV.
df
% CV.
df
% CV.
df
% CV.
df
HCT (%)
#1
33.67
1.28
28
0
14
28.47
0.94
26
0.66
14
#2
33.87
0.92
22
0
11
28.49
1.10
22
0
11
#3
34.75
0.51
24
0
12
29.34
0.82
24
0
12
HGB (g/dL)
#1
11.85
0.47
28
0.32
14
10.09
0.68
28
0
14
#2
11.96
0.56
22
0
11
10.24
0.43
22
0.21
11
#3
12.15
0.58
24
0
12
10.35
0.61
24
0
12
PLT (× 10
9
/L)
#1
386.89
5.15
28
5.09
14
141.05
6.03
28
4.14
14
#2
387.91
6.69
22
8.88
11
128.50
5.38
22
2.96
11
#3
330.37
4.50
24
1.09
12
129.38
4.74
24
2.70
12
WBC
(× 10
9
/L)
#1
9.55
9.07
28
6.70
14
19.06
9.05
28
0
14
#2
7.36
7.24
22
4.31
11
16.09
4.75
22
6.15
11
#3
7.69
8.11
24
2.78
12
15.51
5.47
24
3.83
12
GRAN (× 10
9
/L)
#1
6.15
9.30
28
5.76
14
10.29
8.28
28
0
14
#2
4.67
8.58
22
7.33
11
8.01
3.66
22
4.08
11
#3
4.94
8.39
24
3.61
12
8.27
4.73
24
3.18
12
LYMPH/MONO
(× 10
9
/L)
#1
3.40
12.05
28
8.95
14
8.77
11.32
28
0
14
#2
2.68
7.60
22
8.21
11
8.07
6.53
22
8.71
11
#3
2.74
11.86
24
4.13
12
7.24
9.09
24
5.49
12
Key to QBC Control Precision Table:
Intra-run precision = variability between duplicate tubes during the same run.
Inter-run precision = variability between two runs per day over multiple days.
df = degrees of freedom
0 = negative estimate (variance was negative)
Site #1 & Site #2 = POLs
Site #3 = BDPCD