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Bio-Rad PROTEAN® i12™ IEF System User Manual

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PROTEAN i12 IEF System Instruction Manual

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Chapter 7 Troubleshooting

Problem

Cause

Solution

Voltage does not increase
beyond a low value

High levels of ionic contaminants
in rehydration and sample
solutions

Several hours may be needed for
ionic contaminants to leave IPG
strips. Keep salt concentration
below 40 mM

Voltage does not reach the
programmed value or reaches it
very slowly

Programmed voltage may not
be reached due to the sample
composition

No action needed

Ampholyte concentration is
too high. Up to 1% Bio-Lyte

®

ampholytes may be used,
but ampholytes increase
conductivity; therefore, voltage
will be lower with increasing
concentrations

Lower the ampholyte
concentration

Error message appears

Situation-dependent

Shut down the instrument using
the power switch and then
restart it. If this fails to resolve the
issue, contact Bio-Rad Technical
Support