Multichannel Systems MEA Manual - Manual (Page 58)

MEA Manual
58
9.3 Noise on Single Electrodes
The noise level on single electrodes is significantly higher than expected or you see artifact signals.
In the following example (60MEA200/30, filled with PBS (phosphate buffered saline), silver pellet
as bath electrode, shielded), electrodes No. 53, 63, 73, 45, 55, 48, 58 show a high noise level.
Possible causes:
? The electrode or the contact pin of the amplifier may be defective. To test this, do the following.
1. Open the amplifier and turn the MEA by 90 degrees.
2. Close the amplifier again and start the recording.
If the same electrode in the MEA layout is affected, the amplifier's contact is not ok. If another electrode
is now affected and the previously affected electrode is ok now, the MEA electrode is not ok, but the
amplifier is fine. The following screen shot shows the same MEA than above that has been turned
clockwise by 90 degrees. You see that different channels are now affected, which indicates that the
amplifier is fine but some electrodes on the MEA are defective.
— OR —
 Use the test model probe to test the amplifier. If the noise level is fine without the MEA, bad MEA
electrodes cannot be the cause.