Multichannel Systems MEA Manual - Manual (Page 22)

MEA Manual
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4.10 MEA with 6 Wells: 60-6wellMEA
60-6wellMEA200/30iR-Ti
60-6wellMEAs are MEA chips with six independent culture chambers, separated by a macrolon ring. Inside
each well, in between the marked two bars coming out of the circle in the middle of the MEA, there is a
field of nine electrodes with an internal reference electrode. The electrode in the center of the MEA is for
grounding.
60-6wellMEAs are developed, for example, for safety-pharmacological screenings of drug induced
QT-prolongation. Multi Channel System MCS GmbH provides a software solution for these experimental
intentions, the QT-Screen-Lite program. The 60-6wellMEA allows running six experiments with identical
surrounding conditions at once. Two types of macrolon rings are available: Rings with six triangular
chambers and rings with round chambers.
The electrodes of the 60-6wellMEA are from titanium nitride (TiN), the isolation is made up of Silicon nitride
(SiN). Contact pads are from titanium nitride (TiN), and tracks are from titanium (Ti). The diameter of the
electrodes is 30 μm, the distance from centre to centre is 200 μm.
Using 60-6wellMEAs
60-6wellMEAs can be used for a wide variety of applications. They are robust and heat-stabilized. They can
be autoclaved and coated with different procedures for cell and tissue cultures. Generally, they can be used
for acute experiments as well as long-term cultures.