beautypg.com

3 high density mea: 60hdmea – Multichannel Systems MEA Manual User Manual

Page 15

background image

MEA Manual

15

4.3 High Density MEA: 60HDMEA

60HDMEA30/10iR-ITO

10 μm electrodes are arranged in two recording fields with 5 x 6 electrodes each. The interelectrode
spacing is only 30 μm center to center.

The very high electrode density of the two recording fields on a 60HDMEA is only possible by the special
TiN electrode material and production process. This MEA type is especially useful for applications, where
a high spatial resolution is critical, for example, for multitrode analysis.

For example, the very high spatial resolution of the high density MEAs is very useful for recording from
retina ganglia cells. The double recording field can also be used for coculturing two slices, each on one
recording field. The flat, round electrodes are made of titanium nitride (TiN).Tracks and contact pads are
made of transparent indium tin oxide (ITO); insulation material is silicon nitride.

60HDMEA30/10iR-ITO MEAs are available with internal reference electrode.

Using 60HDMEAs

The same material is used for standard MEAs and high density MEAs. Therefore, they are equally robust
and heat-stabilized. They can be autoclaved and coated with different procedures for cell and tissue
cultures.