Bio-Rad Bio-Plex® 200 Systems - Manual (Page 32)

Section 4
Care and Maintenance
Table 6. Summary of Care and Maintenance.
Daily Startup, calibrate, wash between plates, shut down
Weekly Sonicate needle, unclog, check for leaks
Monthly Validation, clean exterior surface
6 months Replace syringe seal, clean ventilation filter
Yearly Replace sheath filter, replace air intake filter
Note: Two long needles are included with the Bio-Plex ® 200 system. While one is being
cleaned, the other can be installed to prevent any downtime from this weekly maintenance.
Proper maintenance and cleaning should be performed in order to preserve the longevity and
reliability of the system.
Regularly As Required
Preventing clogs in the The Start Up, Shut Down, and Wash Between Plates
fluidics system procedures must be strictly followed to prevent
clogging of the fluidics system.
Sheath fluid and waste fluids Replace the sheath fluid and empty the waste container
as required. You must manually monitor the waste
container level. Release the instrument’s pressure by
removing the lid from the sheath fluid container. Add
sheath fluid, filling the sheath fluid container to just
below the air intake. Discard waste fluid by appropriate
means. After closing containers, remove air from the
lines by performing a Start Up.
One must refill sheath and empty the waste after two
full plates are run.
Run a Wash Between Plates function after each plate
is run.
Check for leaks Open all instrument doors and visually inspect for
leaks. If a leak or spill is observed, verify whether it is
coming from the sample needle assembly. Check to
see that the knurled tubing connector is tightened
properly (see Section 3.8). If this is not the source of
the leak, turn off all power to the system, disconnect all
power cords, and contact Bio-Rad Technical Support
for further information.
Sanitize Fill MCV plate with a solution of 10% household
bleach. Place MCV plate in microplate platform.
Choose Shut Down.
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