Bio-Rad Gene Pulser MXcell™ Electroporation System - Manual (Page 57)

Gene Pulser MXcell™ System Manual | Factors Affecting Electroporation
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Resistor Pulse Modulation
The Gene Pulser MXcell electroporation system uses a new system for controlling parallel
resistance. This new system incorporates the function provided by the Gene Pulser MXcell
CE Module, but within the smaller space available in the Gene Pulser MXcell power module.
The new system (called RPM for “resistor pulse modulation”) varies at high frequency the
time a parallel resistance is connected to the output of the Gene Pulser MXcell system. By
changing the duty cycle of this connection time, the effective value of the parallel resistance
can be varied. The selected Gene Pulser MXcell system capacitance averages the resulting
pulse-modulated resistance. This approach requires fewer components, uses less space,
provides a wider resistance range (50-1,500
Ω), and increases flexibility of the Gene Pulser
MXcell system.