Epson SureColor P5000 Commercial Edition 17" Wide-Format Inkjet Printer - Manual (Page 127)

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6. Insert the new cartridge with the arrow facing up and push it in until it clicks into place.
Caution: Do not remove and re-insert cartridges more often than necessary. Doing so can break the
needle valve seal and allow air to enter the ink tubes, damaging the nozzles.
7. Close the ink cartridge cover and push it in until it clicks into place.
Your product begins charging the ink delivery system.
Note: Do not turn off the product during ink charging.
Caution: If you remove an ink cartridge for later use, protect the ink supply area from dirt and dust and
store it in the same environment as the printer. The valve in the ink supply port is designed to contain
any excess ink, but do not touch the ink supply port or surrounding area. Always store ink cartridges with
the label facing up; do not store cartridges upside-down.