Bio-Rad PROTEAN II XL Cell - Manual (Page 22)

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4. With the short glass plate facing the cooling core (and the locating decal on the clamps facing the core),
position the gel sandwich so that the grooves in the upper portion of the clamps are fitted onto the locating
pins on the central cooling core.* The gel sandwich should be positioned at an angle of ≤20° with the
cooling core. Keeping this angle to a minimum and lubricating the gasket will prevent distortion of the
gasket while the sandwich slides into place.
*Note: The locating pins on the central cooling core must be tightly secured in place to insure optimal
pressure during operation. If these pins are vibrated loose during transport or repeated use, the decrease
in pressure on the clamp can be enough to allow the cell to leak. If the pins are loose, they can be gently
tightened using a coin or screwdriver.
5. With your fingers below the latch on the cooling core and your thumbs resting on the clamps, gently push
the gel sandwich onto the cooling core with one simple motion. The upper edge of the short inner glass
plate should be butted against the notches of the U-shaped gasket, and the tabs of each clamp should
be held securely against the latch assemblies on both sides of the cooling core.