K-Patents PR-23 for K-Patents - Manual (Page 27)

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27
5
Use of Laboratory Test Cuvette LTC:
Continuous sampling
The Laboratory Test Cuvette LTC for continuous sampling can be used for further testing
of samples in pilot scale-up trials for instance in drug formulation or process scale-up. The
typical size of such laboratory batch is 3-10 liters (100 - 300 fl oz).of a liquid.
With continuous sampling the liquid sample is circulated by an external sample pump so the
LTC mixer is not required. Liquid line hoses are used to connect the external sample pump
to the continuous sampling chamber inlet and outlet.
5.1 Assembly of continuous sampling Laboratory Test
Cuvette
The Laboratory Test Cuvette LTC for continuous sampling is assembled using the same
components as the LTC for static sampling, except for the replacement of the static sampling
chamber with the continuous sampling chamber (Figure 5.1). The continuous sampling
chamber has two pipes at the top for inlet and outlet hose connections to an external
sample pump.
1 2
Continuous sampling
chamber
Compression
spring
Temperature control
fluid - inlet
Temperature control
fluid - outlet
O-ring
21x2 EPDM
O-ring
20.2x3 EPDM
Outer casing
Grove for
O-ring
Figure 5.1 K-Patents Laboratory Cuvette LTC for continuous sampling: Components and assembly
of sample chamber.