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Bio-Rad Bio-Plex System Validation and Calibration Tools User Manual

Page 19

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12. Repeat procedure if values are not within the specification range. If values

are again not within acceptable specification ranges, contact Bio-Rad
technical support for assistance.

10.5 Validation of Classify Efficiency

Procedure

1.

If not already done, follow the procedure for start-up and calibration of the
Bio-Plex system.

N

No

otte

e:: B

Be

e s

su

urre

e tto

o c

ca

alliib

brra

atte

e iim

mm

me

ed

diia

atte

elly

y b

be

effo

orre

e v

va

alliid

da

attiio

on

n.. IIff y

yo

ou

u a

arre

e u

us

siin

ng

g B

Biio

o--P

Plle

ex

x

M

Ma

an

na

ag

ge

err 4

4..0

0//4

4..1

1,, u

us

se

e e

eiitth

he

err tth

he

e h

hiig

gh

h o

orr llo

ow

w R

RP

P1

1 tta

arrg

ge

ett ffo

orr C

Ca

all2

2 c

ca

alliib

brra

attiio

on

n

d

de

ep

pe

en

nd

diin

ng

g o

on

n tth

he

e tty

yp

pe

e o

off a

as

ss

sa

ay

y b

be

eiin

ng

g p

pe

errffo

orrm

me

ed

d.. IIff y

yo

ou

u a

arre

e u

us

siin

ng

g B

Biio

o--P

Plle

ex

x

M

Ma

an

na

ag

ge

err 5

5..0

0,, tth

he

e c

ca

alliib

brra

attiio

on

n iis

s d

do

on

ne

e o

on

n llo

ow

w R

RP

P1

1 tta

arrg

ge

ett.. S

Se

elle

ec

cttiio

on

n o

off h

hiig

gh

h R

RP

P1

1

tta

arrg

ge

ett iis

s d

do

on

ne

e iin

n tth

he

e v

va

alliid

da

attiio

on

n s

sc

crre

ee

en

n..

2.

Remove the classify validation bead set from 4°C storage and vortex each
bottle for 30 sec.

3.

Place 5 drops of each classify bead into the corresponding classify well
labeled as A, B, C, D, and E in the MCV plate.

4.

Store stock vials at 4°C as soon as possible after use. Protect beads from
light.

5.

Select IIn

ns

sttrru

um

me

en

ntt from the main menu. Select V

Va

alliid

da

attiio

on

n from the pull-down

menu.

6.

Enter the User name and select control number. Select C

Clla

as

ss

siiffy

y V

Va

alliid

da

attiio

on

n.

Select OK. The following dialog box will appear (Figure 10):

Fig. 10. Classify validation dialog.

7.

Select the Eject button to eject the plate holder.

8.

Place the MCV plate on the microplate platform.

9.

Select O

OK

K to start the classify validation procedure.

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