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Leica Biosystems RM2235 User Manual

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Instructions for Use V 1.8 RevC – 09/2013

Table of Contents

1.

Important Information ............................................................................................................... 4

2. Safety ........................................................................................................................................... 5

2.1

Safety notes ................................................................................................................................... 5

2.2 Warnings ........................................................................................................................................ 5

2.3

Integrated safety devices............................................................................................................ 8

3.

Instrument Components and Specifications ....................................................................... 10

3.1

Overview — instrument components ..................................................................................... 10

3.2

Instrument specifications.......................................................................................................... 11

3.3

Technical Data ............................................................................................................................ 12

4.

Instrument Setup ...................................................................................................................... 13

4.1

Standard delivery ........................................................................................................................ 13

4.2

Installation site requirements ................................................................................................... 13

4.3

Unpacking and installation........................................................................................................ 14

4.4

Assembling the handwheel....................................................................................................... 16

4.5

Inserting the universal cassette clamp................................................................................... 17

4.6

Inserting the knife holder .......................................................................................................... 18

5. Operation ................................................................................................................................... 19

5.1

Operating elements and their functions ................................................................................. 19

5.1.1 Section thickness setting .......................................................................................................... 19

5.1.2 Coarse driving wheel ................................................................................................................. 19

5.1.3 Specimen retraction................................................................................................................... 20

5.1.4 Mechanical trimming function ................................................................................................. 20

5.1.5 Specimen holder with precision orientation .......................................................................... 21

5.2

Adjusting the clearance angle ................................................................................................. 22

5.3

Fine adjustment of the force balance...................................................................................... 23

5.4

Clamping the specimen ............................................................................................................. 24

5.5

Clamping the knife / disposable blade .................................................................................... 24

5.6 Sectioning .................................................................................................................................... 25

5.7

Changing the specimen or interrupting sectioning .............................................................. 26

5.8

Finishing the daily routine ......................................................................................................... 26

6.

Optional Accessories .............................................................................................................. 27

6.1

Assembly for fixture for specimen clamps ............................................................................. 27

6.1.1 Rigid fixture for specimen clamps ........................................................................................... 27

6.1.2 Directional fixture for specimen clamps................................................................................. 27