Asus M4A78T-E - Manual (Page 24)

2-4 Chapter 2: Hardware information
Chapter 2
2.2.3 Placement direction
When installing the motherboard, make sure that you place it into the chassis in the correct orientation.
The edge with external ports goes to the rear part of the chassis as indicated in the image below.
2.2.4 Screw holes
Place nine (9) screws into the holes indicated by circles to secure the motherboard to the chassis.
DO NOT overtighten the screws! Doing so can damage the motherboard.
Place this side towards
the rear of the chassis