Metrohm 853 IC CO2 Suppressor - Manual (Page 25)

5.4 Validation / GLP
853 CO
2
Suppressor / Instructions for Use 8.853.8001EN
19
5.4 Validation / GLP
GLP (Good Laboratory Practice) requires, among other things, that the
precision and correctness of analytical instruments is checked at regu-
lar intervals by using SOPs (Standard Operating Procedures, SOP). An
example of such a standard operating procedure is available from
Metrohm under the title «Application Bulletin No. 277 – Validation of
Metrohm Ion Chromatography Systems by using Standard Oper-
ating Procedures (SOP)». This SOP can be adapted for your ion
chromatography system and used for its validation.
The 853 CO
2
Suppressor must be included as a part of the whole ion
chromatography system, whose most important components include
the pumps, separation columns, detector and evaluation system, in the
all-embracing validation of the whole system.
Please contact your local Metrohm agency in order to receive support
in validating your 853 CO
2
Suppressor. It can also provide you with
validation documentation which will help you to carry out your installa-
tion qualification (IQ) and operational qualification (OQ).
Further information about QA, GLP and validation can also be found in
the brochure «Quality management with Metrohm» which is also ob-
tainable from your local Metrohm agency.
Checking the electronic and mechanical assemblies of Metrohm in-
struments can and should be undertaken within the framework of regu-
lar servicing by Metrohm technicians.