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C.B.S. Scientific FCU-1000 User Manual

Page 4

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1.3 System Overview

The 3-D Flow Chamber Device is a specialized laminar flow chamber that enables the unique ability

to quantitate cellular motility through a semi-permeable membrane in the presence of shear stress.

Relevant applications for the 3-D Flow Chamber Device include transmigration, chemotaxis, vascular

permeability, and complex in vitro modeling of 3D cell cultures such as the blood brain barrier. Fur-

ther, it can be used to hold material coupons in place of the membranes for analysis of biofilm activity.

1.4 System Contents

The following components ship with the 3-D Flow Chamber Device.

Complete System Includes:

• Flow Chamber Device with 3 reservoirs

• 3 upper membrane inserts

• 3 lower membrane inserts

• Tubing and connectors

• Carrying tray

• Respirator to allow gas exchange and bubble escape