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4 256 thin mea, Onnecting the usb-mea256-system – Multichannel Systems USB-MEA256-System Manual User Manual

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USB-MEA256-System

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4.4 256 Thin MEA

The glass part of 256 Thin MEAs are only 180 μm "thick", ideally suited for high-resolution
imaging. 256ThinMEAs are like standard MEAs, but the electrodes are embedded in a very
thin and delicate glass substrate on a robust ceramic carrier. The thin glass allows the use
of oil immersion objectives with a high numerical aperture.

Like 256MEAs, 252 electrodes are arranged in a 16 x 16 layout grid with electrode diameter
of 30 μm, and interelectrode distance of 200 μm (256ThinMEA200/30-ITO).

256ThinMEAs are heat-stabilized and can be autoclaved. They can also be coated with different
procedures for cell and tissue cultures. They should be handled with great care because of the
thin and delicate recording area. Please see chapter "Data Sheet 256ThinMEA" in the Appendix.

4.5 256-9well

MEA

A special MEA layout for the USB-MEA256-System is available, the 256-9wellMEA for
using together with a 9 well macrolon quadrate. The 9 wells allow, for example drug screening
experiments, with up to 9 compounds at a time. The 256-9wellMEA is in principle constructed
like the 256MEA, but the electrodes are clustered. There are 23 recording electrodes with
a diameter of 30 μm, two bigger recording or stimulation electrodes (2 x 50 μm), and one
big reference electrode per each well. Please see chapter "Data Sheet 256-9wellMEA"
in the Appendix.

ONNECTING THE USB-MEA256-SYSTEM