Immunoreactivity – normal panel – Leica Biosystems Bond Oracle HER2 IHC System User Manual
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Leica Biosystems Bond Oracle HER2 IHC System Instructions for Use TA9145 EN-CE-Rev_E 18/06/2013
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Immunoreactivity – Normal Panel
Normal Tissue Type
Staining Pattern
HER2 Primary Antibody
HER2 Negative Control
Adrenal
Negative
Negative
Brain, Cerebellum
Negative
Negative
Brain, Cerebrum
Negative
Negative
Breast
Negative
Negative
Bone Marrow
Negative
Negative
Colon
Negative
Negative
Esophagus
Negative
Negative
Eye
Negative
Negative
Hypophysis
Moderate cytoplasmic staining
observed in hypophyseal cells (1/3)
Negative
Kidney
Negative
Negative
Larynx
Negative
Negative
Liver
Negative
Negative
Lung
Negative
Negative
Mesothelium
Negative
Negative
Ovary
Negative
Negative
Pancreas
Negative
Negative
Parathyroid
Negative
Negative
Peripheral Nerve
Negative
Negative
Prostate
Negative
Negative
Salivary Gland
Negative
Negative
Skin
Negative
Negative
Small Intestine
Negative
Negative
Spleen
Negative
Negative
Stomach
Weak cytoplasmic staining observed in
gastric glands (2/3)
Negative
Striated Muscle
Negative
Negative
Testis
Negative
Negative
Thymus
Negative
Negative
Thyroid
Negative
Negative
Tonsil
Negative
Negative
Uterine Cervix
Negative
Negative
Uterus
Negative
Negative
Table 9. Normal Panel Staining