Labconco FreeZone Clear Stoppering Chambers - Manual (Page 18)

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Chapter 3: Getting Started
Product Service: Domestic 1-800-522-7658, International 816-333-8811
Chemical Resistance of Freeze
Dryer Components
The FreeZone Freeze Dry System and Clear Stoppering Chamber
are designed to be chemically resistant to most compounds that are
commonly used in freeze drying processes. However, by
necessity, the Freeze Dryer is comprised of a number of different
materials, some of which may be attacked and degraded by certain
chemicals. The degree of degradation is dependent on the
concentration and exposure duration. Some of the major
components of the FreeZone Freeze Dry System that are
susceptible to degradation are as follows:
Acids Buffers Solvents
Component Material Acetic Acid 20
%
Formic Acid Trifluo
roa
cetic Acid
(TFA)
Ca
lcium Chloride
Sodium
Ph
os
phate
Acetone Acetonittirle C
arbon Tet
rochlo
ride
Cycl
ohe
xane
D
iox
ane
Methy
l t-Butyl
Ether (BTBE)
Pyridine
Valve Stem Acetal C D D D D
Clear Chamber
Top & Bottom Acrylic D D D D
Hoses, Gaskets
& Valve
Bodies Neoprene C D D C C D D D C D
Flask Top Silicon
Rubber C D D D D D C D
Chamber &
Fittings Stainless
Steel C
* An accessory glass lid is available for the Freeze Dry System.
C – Moderate degradation; Limited use.
D – Severe degradation; infrequent use recommended; immediate
thorough cleaning required.