Introduction and intended use – ChemoMetec NC-200 User Manual
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Introduction and intended use
991-0203 Rev. 1.1 Sep. 2012 xi
Introduction and intended use
The NucleoCounter NC-200 is a compact cell-counter intended to be used for precise cell
counting within the life-science and pharmaceutical markets. The NucleoCounter NC-200
system is intended for research use only, not for diagnostic use. The NucleoCounter NC-
200 uses disposable cassettes from ChemoMetec A/S.
The NucleoCounter NC-200 is a highly advanced cell counter based on fluorescence
microscopy using CMOS camera technology with low magnification and advanced image
analysis. Different properties of the individual cells can be analyzed with the 3 integrated
light sources (365nm, 500nm and dark field) and with 2 emission bands. Spatial position is
maintained from filter to filter enabling direct comparison of the different parameters
detected or quantified on each individual cell. The low magnification (x1.3) guarantees a
high analysis volume and thus ensures a high statistical performance.
Specially designed sample illumination ensures homogeneous illumination at the complete
measuring area and thereby accurate quantification of fluorescence signal is achieved.
Since no tubes, valves, hoses etc. are present the instrument is virtually service and
maintenance free.
The NucleoCounter NC-200 is improved in relation to NucleoCounter NC-100 and shares
some of the strong features with the NucleoCounter NC-3000. In normal viability analysis
the sample volume is as high as 1.4 µl and the ability to detect cell s in clusters is also
available.
The NucleoCounter NC-200 part number at ChemoMetec A/S is 900-0201.