BUCHI NIRFlex N-500 - Manual (Page 35)

4 Description of function
35 NIRFlex N-500 Operation Manual, Version F
4 .6 .12 NIRFlex Solids Transmittance
NIRFlex Solids Transmittance
It is a major request described in the pharmacopoeias to ensure consistency of dosage units; each
unit in a batch should have active ingredient content within a narrow range around the label claim.
Traditionally these analyses are made using HPLC determining only the active content, which is time
consuming and very costly. The speed, efficiency, and cost situation can be very much improved by
NIR spectroscopy.
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a Aperture 3 mm
b Sample
c Detector
d Optic 3
e Sample plate
f Magnetic coding
g Magnetic sensor
h Light barrier i Stepper motor
j Optic 1
k Aperture
l Mirror
m Optic 2
n Status LED
o START button
p STOP button
Functional principle of NIRFlex Solids Transmittance