Bio-Rad Bio-Scale™ Mini UNOsphere SUPrA™ Affinity Cartridges - Manual (Page 5)

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Section 1
Introduction
UNOsphere SUPrA™ media are affinity chromatography support based on
recombinant protein A. The media are designed for process-scale purification of
monoclonal antibodies. The protein A ligand is produced in E. coli without the use of
material from animal origin. The UNOsphere base bead is a macroporous polymeric
bead that is designed for robust and scaleable process applications. See Table 1 in
the next section for the technical description of the product.
The outstanding flow pressure performance of UNOsphere chromatography media
allows its use in large-scale process applications. The flow characteristics of
UNOsphere SUPrA can be found in Figure 1 in section 2 of this manual.
UNOsphere SUPrA affinity chromatography media come with full regulatory support
and are backed by the support of Bio-Rad’s global application and development
team.
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