Apple iPod shuffle (4th generation) - Manual (Page 23)

Chapter 5 Storing Files on iPod shuffle 23
Preventing iTunes from opening automatically
You can keep iTunes from opening automatically when you connect iPod shuffle to your computer.
Prevent iTunes from opening automatically:
1 Connect iPod shuffle to your computer.
2 In iTunes, select iPod shuffle in the list of devices, then click Summary.
3 Under Options, deselect “Open iTunes when this iPod is connected.”
4 Click Apply.