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Siemens Mobile User Manual

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75

U.S. FDA

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R issue

date: 040413

left page (75)

of CF62 Leopard TMO SUG us, A31008-H6050-A40-1-4A19 (02.06.2004, 16:08)

National Cancer Institute is expected

to bear on the accuracy and repeat-

ability of these results.

1

2. Researchers conducted a large

battery of laboratory tests to assess

the effects of exposure to mobile

phone RF on genetic material. These

included tests for several kinds of

abnormalities, including mutations,

chromosomal aberrations, DNA

strand breaks, and structural

changes in the genetic material of

blood cells called lymphocytes. None

of the tests showed any effect of the

RF except for the micronucleus

assay, which detects structural

effects on the genetic material. The

cells in this assay showed changes

after exposure to simulated cell

phone radiation, but only after

24 hours of exposure. It is possible

that exposing the test cells to radia-

tion for this long resulted in heating.

Since this assay is known to be sensi-

tive to heating, heat alone could

have caused the abnormalities to

occur. The data already in the litera-

ture on the response of the micronu-

cleus assay to RF are conflicting.

Thus follow-up research is neces-

sary.

2

FDA is currently working with gov-

ernment, industry, and academic

groups to ensure the proper follow-

up to these industry-funded research

findings. Collaboration with the Cel-

lular Telecommunications Industry

Association (CTIA) in particular is

expected to lead to FDA providing

research recommendations and sci-

entific oversight of new CTIA-funded

research based on such recommen-

dations.
Two other studies of interest have

been reported recently in the litera-

ture:
• Two groups of 18 people were

exposed to simulated mobile

phone signals under laboratory

conditions while they performed

cognitive function tests. There

were no changes in the subjects'

ability to recall words, numbers,

or pictures, or in their spatial

memory, but they were able to

make choices more quickly in one

visual test when they were

exposed to simulated mobile

phone signals. This was the only

change noted among more than

20 variables compared.

3

• In a study of 209 brain tumor

cases and 425 matched controls,

there was no increased risk of

brain tumors associated with

mobile phone use. When tumors

did exist in certain locations, how-

ever, they were more likely to be

on the side of the head where the

mobile phone was used. Because

this occurred in only a small num-

ber of cases, the increased likeli-

hood was too small to be statisti-

cally significant.

4

In summary, we do not have enough

information at this point to assure

the public that there are, or are not,