ITC Hemochron Response Whole Blood Coagulation System User Manual
Page 3

3
PRINCIPLES OF OPERATION
Refer to the HEMOCHRON Response Whole Blood Coagulation System Operator's Manual for a complete
description of the HEMOCHRON Response Whole Blood Coagulation System.
Once the HEMOCHRON RxDx Analysis Module is installed on the HEMOCHRON Response, an RxDx case is
automatically initiated whenever the operator runs an HRT, PRT, or PDA-O test or manually selects the
RxDx menu.
Each RxDx case is tracked by a numeric Patient ID (PID). Once a PID is entered, it is applied to tests in
both wells. At the outset of the case, the operator enters the PID plus the patient's height, weight and gender
(for calculating blood volume). Calculations performed by the system for determining patient blood
volume, bolus heparin dose, additional heparin dose, and protamine dose are summarized below.
Definitions and Terms
The following acronyms and abbreviations are used in this manual, instrument screens and printouts:
ACT
Activated clotting time (FTCA510/FTK-ACT)
AdditionalHepDose/Addl Hep
Additional heparin dose (units)
Base ACT
Baseline ACT (seconds)
Bld Vol, Blood Vol
Blood volume (mL)
Bolus Hep
Bolus heparin dose (units)
CalcDse
Calculated heparin dose (units)
Cur ACT
Most recent ACT result
EstBV
Estimated blood volume (mL)
Hep Gvn
Heparin dose given to the patient (units)
Hep Lvl
Patient heparin level (units/mL or mg/kg)
HiTT
High Dose Thrombin Time
HRT
Heparin Response Time (R-HRT480P/R-HRT480PK)
OID
Operator Identification Number
Pat Info
Patient demographics information
PDA-O
Protamine Dose Assay - Orange (PDAO/PDAOK)
PID
Patient Identification Number
PIN
Operator Personal Identification Number
PostBolusACT
ACT result following bolus heparin dose
ProtDose
Protamine dose (mg)
PRT
Protamine Response Time (R-PRT200/R-PRT200K)
(R-PRT400/R-PRT400K)
Pump Hep
Amount of heparin added to the pump (units)
QC
Quality Control
Tot Hep/THep
Calculated total heparin dose given, including bolus dose
heparin in the pump and additional heparin given (units)