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Bio-Rad Bio-Rex® 70 Cation Exchange Resins User Manual

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Section 1
Introduction

Bio-Rex 70 resin is a weakly acidic cation

exchanger. This resin is used for the purification and
fractionation of peptides, proteins, antibiotics, and other
cationic molecules.

Section 2
Technical Description

Bio-Rex 70 resin is available as both Analytical

Grade and Biotechnology Grade resin. The Analytical
Grade Bio-Rex 70 resin has been exhaustively sized,
purified, and converted to make it suitable for accurate,
reproducible analytical techniques. Biotechnology Grade
Bio-Rex 70 resin is an Analytical Grade resin which is
certified to contain less than 100 microorganisms per
gram of resin.

The resin contains carboxylic acid exchange groups

on a macroreticular acrylic polymer lattice. The high
porosity of the resin allows large protein molecules to
penetrate the pores and have access to the exchange sites
located throughout the matrix. In an ion exchange
procedure the counterions on the resin are replaced by

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