Penn-Century IA-1B-R for Rat - Manual (Page 4)

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KEY FEATURES:
MicroSprayer® Aerosolizer (liquid) - Model IA-1B
May be operated with either a gas-tight 0.5ml precision
glass syringe
or a 1ml polycarbonate syringe
§ The Penn-Century MicroSprayer® Aerosolizer is the only commercially available air-
free intratracheal aerosol delivery technology.
§ It can be used to administer precise doses of aerosol for intratracheal, intranasal or
other in vivo or in vitro applications.
§ The devices have been shown to successfully administer a wide range of pharmaceutical and
biologic agents, as well as toxicological, bacterial and viral materials.
§ The MicroSprayer® Aerosolizer can administer liquids, solutions or particle suspensions,
including nanoparticle and microparticle solutions.
§ The MicroSprayer® Aerosolizer - Model IA-1B is made of rigid 19-gage stainless steel
tubing and other chemically resistant components, and is designed to be sterilized and re-used.
§ Patented components in the tip of the device help to generate an aerosol when used
with the gas-tight syringe provided.
§ The hub of the MicroSprayer® Aerosolizer - Model IA-1B is luer hub. It can be operated
with either a gas-tight 0.5 ml precision glass syringe (sold separately) or a 1 ml polycarbonate
syringe (provided). The Model IA-1B operates at 700 pounds per square inch (psi) of manual
pressure.
§ Standard lengths of the device are typically made with a 120-degree bend to permit
the user to keep their hand out of the line of sight to the epiglottis.
§ For intratracheal use, the length of portion that is inserted into the trachea is designed to
reach from the incisors to above the carina. For use in rat, the intratracheal portion is 2” after
the bend. For use in guinea pig, it is 3” after the bend.
§ Custom lengths are available for straight, longer or shorter applications, and for
insertion into the trachea or into the lung via an endotracheal tube or bronchoscope.
§ For best results, and to avoid injury to the animal, the tip of the MicroSprayer®
Aerosolizer must be positioned so that the tip is near to – but not touching the carina.
§ Particle size range: Mass Median Diameter of 25-30 µm (microns) NOTE: Particles
analyzed with water using laser defraction method.