KD Scientific 35 Ventilator - Manual (Page 10)

8
KDS35 Small Animal Ventilator
Pump Operation:
(continued)
SELECTION OF RATE AND VOLUME
Refer to the Ventilator Graph (below) to select the appropriate tidal volume and respiration
rate as a function of animal body weight. As a rough guide an adult rat will weigh between
200 and 500 grams with tidal volumes between 0.6 to 1.25 cm3 with respiration rates
between 66 to 210 breaths/min. The average rate is 100 breaths/min. For most rodents the
5 cc cylinder will be adequate. For larger animals it will be necessary to change the cylinder.
100
150
200
300
400
500
40
50
60
80
15
20
10
30
8
4
5
6
2
3
1
0.5
0.6
0.8
0.4
70 100 200 300 400 1 800 600 3 2 4 5 15 10 8 6 20 30 40
100
90
70
80
60
50
40
Breaths per Minute: 10
70 100 200 300 400 1 800 600 3 2 4 5 15 10 8 6 20 30 40
100
150
200
300
400
40
50
60
80
15
20
10
30
8
4
5
6
2
3
1
0.5
0.6
0.8
0.4
500
40
(Grams) Animal Body Weight (Kilograms)
Ti
da
lV
ol
um
e
(m
lA
m
bi
en
tT
em
pe
ra
tu
re
)
30
25
20
15
Ventilator Graph: Tidal Volume vs. Weight & Rate for Laboratory Mammals in Resting State.
(Apparatus dead space must be added)