I.R.I.S. Readiris 14 for Windows User Guide - Manual (Page 58)

Readiris TM 14 – User Guide
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If you do not find your exact scanner in the list, do not select a
similar profile. Instead, select a universal Twain profile. Different
Twain profiles are available:
Select when you are using a
regular, flatbed scanner.
Select (User interface) if you
want to use your scanner user interface to scan documents
instead of Readiris.
Select
when you are using a duplex scanner, which scans both the
front and backside of a page.
Configure
Click Configure to select your scanner driver. Selecting the
correct scanner driver is required for Readiris to be able to
communicate with the scanner.
If you do not see your scanner listed in the Select Source window,
then your scanner driver has not been installed properly. Re-install
your scanner driver before trying to configure it in Readiris. The
scanner driver can usually be found on the website of your scanner
manufacturer.