Asus RS500A-E6/PS4 - Manual (Page 58)

4-10 Chapter 4: Motherboard information
5. Thermal sensor cable connectors (3-pin TR1, TR2)
These connectors are for temperature monitoring. Connect the thermal
sensor cables to these connectors and place the other ends to the devices,
which you want to monitor temperature.
6. CPU, front and rear fan connectors
(4-pin CPU_FAN1, CPU_FAN2, FRNT_FAN1, FRNT_FAN2, FRNT_FAN3,
FRNT_FAN4, FRNT_FAN5, REAR_FAN1)
The fan connectors support cooling fans of 350 mA–740 mA (8.88 W max.)
or a total of 3.15 A–6.66 A (53.28 W max.) at +12V. Connect the fan cables to
the fan connectors on the motherboard, ensuring that the black wire of each
cable matches the ground pin of the connector.
• DO NOT forget to connect the fan cables to the fan connectors. Insufficient
air flow inside the system may damage the motherboard components.
• These are not jumpers! DO NOT place jumper caps on the fan connectors!
• All fans feature the ASUS Fan Speed technology.