MEGUIAR'S G77 - Manual (Page 6)

G77, Gold Class Spray Wax (22-66A): G7716
__________________________________________________________________________________________
Page: 6 of 11
Acute Toxicity
Name Route Species Value
Overall product Ingestion No data available; calculated ATE >5,000 mg/kg
Mixture of: 5-chloro-2-methyl-4-isothiazolin-3-one and 2-
methyl-4-isothiazolin-3-one (3:1) Dermal Rabbit LD50 87 mg/kg
Mixture of: 5-chloro-2-methyl-4-isothiazolin-3-one and 2-
methyl-4-isothiazolin-3-one (3:1) Inhalation-
Dust/Mist
(4 hours) Rat LC50 0.33 mg/l
Mixture of: 5-chloro-2-methyl-4-isothiazolin-3-one and 2-
methyl-4-isothiazolin-3-one (3:1) Ingestion Rat LD50 40 mg/kg
ATE = acute toxicity estimate
Skin Corrosion/Irritation
Name Species Value
Mixture of: 5-chloro-2-methyl-4-isothiazolin-3-one and 2-methyl-4-isothiazolin-
3-one (3:1) Rabbit Corrosive
Serious Eye Damage/Irritation
Name Species Value
Mixture of: 5-chloro-2-methyl-4-isothiazolin-3-one and 2-methyl-4-isothiazolin-
3-one (3:1) Rabbit Corrosive
Skin Sensitisation
Name Species Value
Mixture of: 5-chloro-2-methyl-4-isothiazolin-3-one and 2-methyl-4-isothiazolin-
3-one (3:1) Human
and
animal Sensitising
Photosensitisation
Name Species Value
Mixture of: 5-chloro-2-methyl-4-isothiazolin-3-one and 2-methyl-4-isothiazolin-
3-one (3:1) Human
and
animal Not sensitizing
Respiratory Sensitisation
Name Species Value
Germ Cell Mutagenicity
Name Route Value
Mixture of: 5-chloro-2-methyl-4-isothiazolin-3-one and 2-methyl-4-isothiazolin-
3-one (3:1) In vivo Not mutagenic
Mixture of: 5-chloro-2-methyl-4-isothiazolin-3-one and 2-methyl-4-isothiazolin-
3-one (3:1) In Vitro Some positive data exist, but the data are not
sufficient for classification
Carcinogenicity
Name Route Species Value
Mixture of: 5-chloro-2-methyl-4-isothiazolin-3-one and 2-methyl-
4-isothiazolin-3-one (3:1) Dermal Mouse Not carcinogenic
Mixture of: 5-chloro-2-methyl-4-isothiazolin-3-one and 2-methyl-
4-isothiazolin-3-one (3:1) Ingestion Rat Not carcinogenic
Reproductive Toxicity
Reproductive and/or Developmental Effects
Name Route Value Species Test result Exposure
Duration
Mixture of: 5-chloro-2-methyl-4-
isothiazolin-3-one and 2-methyl-4-
isothiazolin-3-one (3:1) Ingestion Not toxic to female reproduction Rat NOAEL 10
mg/kg/day 2 generation
Mixture of: 5-chloro-2-methyl-4-
isothiazolin-3-one and 2-methyl-4-
isothiazolin-3-one (3:1) Ingestion Not toxic to male reproduction Rat NOAEL 10
mg/kg/day 2 generation