MEGUIAR'S M10 - Manual (Page 9)

M10, Plastic Polish (original formulation): M1008
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Page: 9 of 15
isothiazol-3-one
Specific Target Organ Toxicity - repeated exposure
Name Route Target Organ(s) Value Species Test result Exposure
Duration
White mineral oil
(petroleum) Ingestion hematopoietic
system Some positive data exist, but the
data are not sufficient for
classification Rat NOAEL
1,381
mg/kg/day 90 days
White mineral oil
(petroleum) Ingestion liver | immune
system Some positive data exist, but the
data are not sufficient for
classification Rat NOAEL
1,336
mg/kg/day 90 days
Glycerin Inhalation respiratory system Some positive data exist, but the
data are not sufficient for
classification Rat NOAEL 3.91
mg/l 14 days
Glycerin Inhalation heart | liver | kidney
and/or bladder All data are negative Rat NOAEL 3.91
mg/l 14 days
Glycerin Ingestion endocrine system |
hematopoietic
system | liver |
kidney and/or
bladder All data are negative Rat NOAEL
10,000
mg/kg/day 2 years
Aspiration Hazard
Name Value
White mineral oil (petroleum) Aspiration hazard
Distillates (petroleum), hydrotreated light Aspiration hazard
Please contact the address or phone number listed on the first page of the SDS for additional toxicological information
on this material and/or its components.
SECTION 12: Ecological information
The information below may not be consistent with the material classification in Section 2 if specific ingredient classifications
are mandated by a competent authority. Additional information leading to material classification in Section 2 is available
upon request. In addition, environmental fate and effects data on ingredients may not be reflected in this section because an
ingredient is present below the threshold for labelling, an ingredient is not expected to be available for exposure, or the data
is considered not relevant to the material as a whole.
12.1. Toxicity
No product test data available.
Material CAS Nbr Organism Type Exposure Test endpoint Test result
Mixture of 5-
chloro-2-
methyl-2H-
isothiazol-3-
one and 2-
methyl-2H-
isothiazol-3-
one 55965-84-9 Rainbow trout Experimental 96 hours LC50 0.07 mg/l
Mixture of 5-
chloro-2-
methyl-2H-
isothiazol-3-
one and 2-
methyl-2H-
isothiazol-3-
one 55965-84-9 Water flea Experimental 48 hours EC50 0.18 mg/l