MEGUIAR'S M10 - Manual (Page 7)

M10, Plastic Polish (original formulation): M1008
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Acute Toxicity
Name Route Species Value
Overall product Ingestion No data available; calculated ATE >5,000 mg/kg
White mineral oil (petroleum) Dermal Rabbit LD50 > 2,000 mg/kg
White mineral oil (petroleum) Ingestion Rat LD50 > 5,000 mg/kg
Distillates (petroleum), hydrotreated light Dermal Rabbit LD50 > 3,160 mg/kg
Distillates (petroleum), hydrotreated light Inhalation-
Dust/Mist
(4 hours) Rat LC50 > 3.0 mg/l
Distillates (petroleum), hydrotreated light Ingestion Rat LD50 > 5,000 mg/kg
Glycerin Dermal Rabbit LD50 estimated to be > 5,000 mg/kg
Glycerin Ingestion Rat LD50 > 5,000 mg/kg
Mixture of 5-chloro-2-methyl-2H-isothiazol-3-one and 2-methyl-
2H-isothiazol-3-one Dermal Rabbit LD50 87 mg/kg
Mixture of 5-chloro-2-methyl-2H-isothiazol-3-one and 2-methyl-
2H-isothiazol-3-one Inhalation-
Dust/Mist
(4 hours) Rat LC50 0.33 mg/l
Mixture of 5-chloro-2-methyl-2H-isothiazol-3-one and 2-methyl-
2H-isothiazol-3-one Ingestion Rat LD50 40 mg/kg
ATE = acute toxicity estimate
Skin Corrosion/Irritation
Name Species Value
White mineral oil (petroleum) Rabbit No significant irritation
Distillates (petroleum), hydrotreated light Rabbit Mild irritant
Glycerin Rabbit No significant irritation
Mixture of 5-chloro-2-methyl-2H-isothiazol-3-one and 2-methyl-2H-isothiazol-3-
one Rabbit Corrosive
Serious Eye Damage/Irritation
Name Species Value
White mineral oil (petroleum) Rabbit Mild irritant
Distillates (petroleum), hydrotreated light Rabbit Mild irritant
Glycerin Rabbit No significant irritation
Mixture of 5-chloro-2-methyl-2H-isothiazol-3-one and 2-methyl-2H-isothiazol-3-
one Rabbit Corrosive
Skin Sensitisation
Name Species Value
White mineral oil (petroleum) Guinea
pig Not sensitizing
Distillates (petroleum), hydrotreated light Guinea
pig Not sensitizing
Glycerin Guinea
pig Not sensitizing
Mixture of 5-chloro-2-methyl-2H-isothiazol-3-one and 2-methyl-2H-isothiazol-3-
one Human
and
animal Sensitising
Photosensitisation
Name Species Value
Mixture of 5-chloro-2-methyl-2H-isothiazol-3-one and 2-methyl-2H-isothiazol-3-
one Human
and
animal Not sensitizing
Respiratory Sensitisation
Name Species Value
Germ Cell Mutagenicity
Name Route Value
White mineral oil (petroleum) In Vitro Not mutagenic
Distillates (petroleum), hydrotreated light In Vitro Not mutagenic