Soundtoys PhaseMistress - Manual (Page 12)

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You can insert as many versions of PhaseMistress as you’d like, just keep in mind
that each one gobbles up certain amount of CPU cycles and can make your computer
start to sweat in terms of what’s left over for other tasks.
Non-Real Time Processing (AudioSuite)
If you want to save computer power, PhaseMistress can also be used to process a
specific region of audio destructively. This is done in ProTools using the AudioSuite
version of PhaseMistress. To do this, first select the region of audio you’d like to
process from the Edit window of Pro Tools. Then choose PhaseMistress from the
AudioSuite menu of ProTools.
Hit the process button to process the selected region with PhaseMistress and to
write the result back to disk. To hear the effect before committing to disk, click on
the preview button.