MEGUIAR'S D120 - Manual (Page 9)

D120, Glass Cleaner Concentrate (22-134A): D12001, D12005, D12025
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2-Butoxyethanol Rabbit Severe irritant
Skin Sensitisation
Name Species Value
Propan-2-ol Guinea
pig Not sensitizing
2-Butoxyethanol Guinea
pig Not sensitizing
Respiratory Sensitisation
Name Species Value
Germ Cell Mutagenicity
Name Route Value
Propan-2-ol In Vitro Not mutagenic
Propan-2-ol In vivo Not mutagenic
2-Butoxyethanol In Vitro Some positive data exist, but the data are not
sufficient for classification
Carcinogenicity
Name Route Species Value
Propan-2-ol Inhalation Rat Some positive data exist, but the data are not
sufficient for classification
2-Butoxyethanol Inhalation Multiple
animal
species Some positive data exist, but the data are not
sufficient for classification
Reproductive Toxicity
Reproductive and/or Developmental Effects
Name Route Value Species Test result Exposure
Duration
Propan-2-ol Ingestion Some positive developmental data exist,
but the data are not sufficient for
classification Rat NOAEL 400
mg/kg/day during
organogenesis
Propan-2-ol Inhalation Some positive developmental data exist,
but the data are not sufficient for
classification Rat LOAEL 9
mg/l during
gestation
2-Butoxyethanol Dermal Not toxic to development Rat NOAEL
1,760
mg/kg/day during
gestation
2-Butoxyethanol Ingestion Some positive developmental data exist,
but the data are not sufficient for
classification Rat NOAEL 100
mg/kg/day during
organogenesis
2-Butoxyethanol Inhalation Some positive developmental data exist,
but the data are not sufficient for
classification Multiple
animal
species NOAEL 0.48
mg/l during
organogenesis
Target Organ(s)
Specific Target Organ Toxicity - single exposure
Name Route Target Organ(s) Value Species Test result Exposure
Duration
Propan-2-ol Inhalation central nervous
system depression May cause drowsiness or
dizziness Human NOAEL Not
available
Propan-2-ol Inhalation respiratory irritation Some positive data exist, but the
data are not sufficient for
classification Human NOAEL Not
available
Propan-2-ol Inhalation auditory system Some positive data exist, but the
data are not sufficient for
classification Guinea
pig NOAEL 13.4
mg/l 24 hours
Propan-2-ol Ingestion central nervous
system depression May cause drowsiness or
dizziness Human NOAEL Not
available poisoning
and/or abuse