MEGUIAR'S D163 - Manual (Page 8)

D163, Tyre & Trim Detailer (24-47A): D16332
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Page: 8 of 14
Mixture of 5-chloro-2-methyl-2H-isothiazol-3-one and 2-methyl-
2H-isothiazol-3-one Ingestion Rat Not carcinogenic
Reproductive Toxicity
Reproductive and/or Developmental Effects
Name Route Value Species Test result Exposure
Duration
Triethanolamine Ingestion Not toxic to development Mouse NOAEL
1,125
mg/kg/day during
organogenesis
Mixture of 5-chloro-2-methyl-2H-
isothiazol-3-one and 2-methyl-2H-
isothiazol-3-one Ingestion Not toxic to female reproduction Rat NOAEL 10
mg/kg/day 2 generation
Mixture of 5-chloro-2-methyl-2H-
isothiazol-3-one and 2-methyl-2H-
isothiazol-3-one Ingestion Not toxic to male reproduction Rat NOAEL 10
mg/kg/day 2 generation
Mixture of 5-chloro-2-methyl-2H-
isothiazol-3-one and 2-methyl-2H-
isothiazol-3-one Ingestion Not toxic to development Rat NOAEL 15
mg/kg/day during
organogenesis
Target Organ(s)
Specific Target Organ Toxicity - single exposure
Name Route Target Organ(s) Value Species Test result Exposure
Duration
Distillates (petroleum),
hydrotreated light Inhalation central nervous
system depression May cause drowsiness or
dizziness NOAEL Not
available
Distillates (petroleum),
hydrotreated light Inhalation respiratory irritation Some positive data exist, but the
data are not sufficient for
classification NOAEL Not
available
Mixture of 5-chloro-2-
methyl-2H-isothiazol-3-
one and 2-methyl-2H-
isothiazol-3-one Inhalation respiratory irritation Some positive data exist, but the
data are not sufficient for
classification similar
health
hazards NOAEL Not
available
Specific Target Organ Toxicity - repeated exposure
Name Route Target Organ(s) Value Species Test result Exposure
Duration
Triethanolamine Dermal kidney and/or
bladder Some positive data exist, but the
data are not sufficient for
classification Multiple
animal
species NOAEL
2,000
mg/kg/day 2 years
Triethanolamine Dermal liver Some positive data exist, but the
data are not sufficient for
classification Mouse NOAEL
4,000
mg/kg/day 13 weeks
Triethanolamine Ingestion kidney and/or
bladder Some positive data exist, but the
data are not sufficient for
classification Rat LOAEL
1,000
mg/kg/day 2 years
Triethanolamine Ingestion liver Some positive data exist, but the
data are not sufficient for
classification Guinea
pig NOAEL
1,600
mg/kg/day 24 weeks
Aspiration Hazard
Name Value
Distillates (petroleum), hydrotreated light Aspiration hazard
Please contact the address or phone number listed on the first page of the SDS for additional toxicological information
on this material and/or its components.
SECTION 12: Ecological information
The information below may not be consistent with the material classification in Section 2 if specific ingredient classifications
are mandated by a competent authority. Additional information leading to material classification in Section 2 is available