MEGUIAR'S D300 User Manual
Page 10

D300, DA Microfiber Correction Compound (21-49D): D30001, D30016, D30032
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Reproductive Toxicity
Reproductive and/or Developmental Effects
Name
Route
Value
Species
Test result
Exposure
Duration
Solvent naphtha (petroleum), medium
aliphatic
Inhalation
Not toxic to development
Rat
NOAEL 2.4
mg/l
during
organogenesis
White mineral oil (petroleum)
Ingestion
Not toxic to female reproduction
Rat
NOAEL
4,350
mg/kg/day
13 weeks
White mineral oil (petroleum)
Ingestion
Not toxic to male reproduction
Rat
NOAEL
4,350
mg/kg/day
13 weeks
White mineral oil (petroleum)
Ingestion
Not toxic to development
Rat
NOAEL
4,350
mg/kg/day
during
gestation
Glycerin
Ingestion
Not toxic to female reproduction
Rat
NOAEL
2,000
mg/kg/day
2 generation
Glycerin
Ingestion
Not toxic to male reproduction
Rat
NOAEL
2,000
mg/kg/day
2 generation
Glycerin
Ingestion
Not toxic to development
Rat
NOAEL
2,000
mg/kg/day
2 generation
Triethanolamine
Ingestion
Not toxic to development
Mouse
NOAEL
1,125
mg/kg/day
during
organogenesis
Mixture of 5-chloro-2-methyl-2H-
isothiazol-3-one and 2-methyl-2H-
isothiazol-3-one
Ingestion
Not toxic to female reproduction
Rat
NOAEL 10
mg/kg/day
2 generation
Mixture of 5-chloro-2-methyl-2H-
isothiazol-3-one and 2-methyl-2H-
isothiazol-3-one
Ingestion
Not toxic to male reproduction
Rat
NOAEL 10
mg/kg/day
2 generation
Mixture of 5-chloro-2-methyl-2H-
isothiazol-3-one and 2-methyl-2H-
isothiazol-3-one
Ingestion
Not toxic to development
Rat
NOAEL 15
mg/kg/day
during
organogenesis
Target Organ(s)
Specific Target Organ Toxicity - single exposure
Name
Route
Target Organ(s)
Value
Species
Test result
Exposure
Duration
Solvent naphtha
(petroleum), medium
aliphatic
Inhalation
central nervous
system depression
May cause drowsiness or
dizziness
Human
and
animal
NOAEL Not
available
Solvent naphtha
(petroleum), medium
aliphatic
Inhalation
respiratory irritation
Some positive data exist, but the
data are not sufficient for
classification
NOAEL Not
available
Solvent naphtha
(petroleum), medium
aliphatic
Inhalation
nervous system
Some positive data exist, but the
data are not sufficient for
classification
Dog
NOAEL 6.5
mg/l
4 hours
Mixture of 5-chloro-2-
methyl-2H-isothiazol-3-
one and 2-methyl-2H-
isothiazol-3-one
Inhalation
respiratory irritation
Some positive data exist, but the
data are not sufficient for
classification
similar
health
hazards
NOAEL Not
available
Specific Target Organ Toxicity - repeated exposure
Name
Route
Target Organ(s)
Value
Species
Test result
Exposure
Duration
Aluminium Oxide
Inhalation
pneumoconiosis |
pulmonary fibrosis
Some positive data exist, but the
data are not sufficient for
classification
Human
NOAEL Not
available
occupational
exposure
Solvent naphtha
(petroleum), medium
Inhalation
nervous system
Some positive data exist, but the
data are not sufficient for
Rat
LOAEL 4.6
mg/l
6 months