MEGUIAR'S M40 - Manual (Page 8)

M40, Vinyl/Rubber Cleaner and Protectant (19-191E): M4001, M4005, M4016
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Reproductive and/or Developmental Effects
Name Route Value Species Test result Exposure
Duration
Propane-1,2-diol Ingestion Not toxic to female reproduction Mouse NOAEL
10,100
mg/kg/day 2 generation
Propane-1,2-diol Ingestion Not toxic to male reproduction Mouse NOAEL
10,100
mg/kg/day 2 generation
Propane-1,2-diol Ingestion Not toxic to development Multiple
animal
species NOAEL
1,230
mg/kg/day during
organogenesis
Mixture of 5-chloro-2-methyl-2H-
isothiazol-3-one and 2-methyl-2H-
isothiazol-3-one Ingestion Not toxic to female reproduction Rat NOAEL 10
mg/kg/day 2 generation
Mixture of 5-chloro-2-methyl-2H-
isothiazol-3-one and 2-methyl-2H-
isothiazol-3-one Ingestion Not toxic to male reproduction Rat NOAEL 10
mg/kg/day 2 generation
Mixture of 5-chloro-2-methyl-2H-
isothiazol-3-one and 2-methyl-2H-
isothiazol-3-one Ingestion Not toxic to development Rat NOAEL 15
mg/kg/day during
organogenesis
Target Organ(s)
Specific Target Organ Toxicity - single exposure
Name Route Target Organ(s) Value Species Test result Exposure
Duration
Propane-1,2-diol Ingestion central nervous
system depression May cause drowsiness or
dizziness Human NOAEL Not
available poisoning
and/or abuse
Trisodium Phosphate Inhalation respiratory irritation May cause respiratory irritation similar
health
hazards NOAEL Not
available
Mixture of 5-chloro-2-
methyl-2H-isothiazol-3-
one and 2-methyl-2H-
isothiazol-3-one Inhalation respiratory irritation Some positive data exist, but the
data are not sufficient for
classification similar
health
hazards NOAEL Not
available
Specific Target Organ Toxicity - repeated exposure
Name Route Target Organ(s) Value Species Test result Exposure
Duration
Propane-1,2-diol Ingestion hematopoietic
system Some positive data exist, but the
data are not sufficient for
classification Multiple
animal
species NOAEL
1,370
mg/kg/day 117 days
Propane-1,2-diol Ingestion kidney and/or
bladder All data are negative Dog NOAEL
5,000
mg/kg/day 104 weeks
Aspiration Hazard
Name Value
Please contact the address or phone number listed on the first page of the SDS for additional toxicological information
on this material and/or its components.
SECTION 12: Ecological information
The information below may not be consistent with the material classification in Section 2 if specific ingredient classifications
are mandated by a competent authority. Additional information leading to material classification in Section 2 is available
upon request. In addition, environmental fate and effects data on ingredients may not be reflected in this section because an
ingredient is present below the threshold for labelling, an ingredient is not expected to be available for exposure, or the data
is considered not relevant to the material as a whole.