MEGUIAR'S D108 - Manual (Page 9)

D108, Super Degreaser (22-160A): D10801, D10805, D10855
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Name Species Value
Sulphonic acids, C14-16-alkane hydroxy and C14-16-alkene, sodium salts Guinea
pig Not sensitizing
Respiratory Sensitisation
Name Species Value
Germ Cell Mutagenicity
Name Route Value
1-propoxypropan-2-ol In Vitro Not mutagenic
Sulphonic acids, C14-16-alkane hydroxy and C14-16-alkene, sodium salts In Vitro Not mutagenic
Carcinogenicity
Name Route Species Value
Sulphonic acids, C14-16-alkane hydroxy and C14-16-alkene,
sodium salts Dermal Rat Not carcinogenic
Sulphonic acids, C14-16-alkane hydroxy and C14-16-alkene,
sodium salts Ingestion Rat Not carcinogenic
Reproductive Toxicity
Reproductive and/or Developmental Effects
Name Route Value Species Test result Exposure
Duration
1-propoxypropan-2-ol Inhalation Some positive developmental data exist,
but the data are not sufficient for
classification Rat NOAEL 3.6
mg/l during
organogenesis
Sulphonic acids, C14-16-alkane hydroxy
and C14-16-alkene, sodium salts Ingestion Not toxic to female reproduction Rat NOAEL 871
mg/kg 2 generation
Sulphonic acids, C14-16-alkane hydroxy
and C14-16-alkene, sodium salts Ingestion Not toxic to male reproduction Rat NOAEL 891
mg/kg 2 generation
Sulphonic acids, C14-16-alkane hydroxy
and C14-16-alkene, sodium salts Ingestion Some positive developmental data exist,
but the data are not sufficient for
classification Rabbit NOAEL 600
mg/kg during
organogenesis
Target Organ(s)
Specific Target Organ Toxicity - single exposure
Name Route Target Organ(s) Value Species Test result Exposure
Duration
1-propoxypropan-2-ol Inhalation central nervous
system depression May cause drowsiness or
dizziness Multiple
animal
species LOAEL 10.8
mg/l 6 hours
1-propoxypropan-2-ol Inhalation respiratory irritation Some positive data exist, but the
data are not sufficient for
classification NOAEL Not
available
1-propoxypropan-2-ol Ingestion central nervous
system depression May cause drowsiness or
dizziness Rat LOAEL
1,770 mg/kg not applicable
Specific Target Organ Toxicity - repeated exposure
Name Route Target Organ(s) Value Species Test result Exposure
Duration
1-propoxypropan-2-ol Inhalation liver | kidney and/or
bladder Some positive data exist, but the
data are not sufficient for
classification Rat NOAEL 9.5
mg/l 11 days
Sulphonic acids, C14-16-
alkane hydroxy and C14-
16-alkene, sodium salts Ingestion liver Some positive data exist, but the
data are not sufficient for
classification Rat NOAEL 500
mg/kg/day 6 months
Sulphonic acids, C14-16-
alkane hydroxy and C14-
16-alkene, sodium salts Ingestion kidney and/or
bladder Some positive data exist, but the
data are not sufficient for
classification Rat NOAEL 500
mg/kg 6 months
Aspiration Hazard