MEGUIAR'S D150 User Manual
Page 8

D150, X-Press Liquid Wax (21-133A), D15001
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Naphtha (petroleum), hydrotreated heavy
Rabbit
No significant irritation
Siloxanes and silicones, di-Me
Rabbit
No significant irritation
Ceramic materials and wares, chemicals
Rabbit
Mild irritant
Mixture of 5-chloro-2-methyl-2H-isothiazol-3-one and 2-methyl-2H-isothiazol-3-
one
Rabbit
Corrosive
Skin Sensitisation
Name
Species
Value
Naphtha (petroleum), hydrotreated heavy
Guinea
pig
Not sensitizing
Mixture of 5-chloro-2-methyl-2H-isothiazol-3-one and 2-methyl-2H-isothiazol-3-
one
Human
and
animal
Sensitising
Photosensitisation
Name
Species
Value
Mixture of 5-chloro-2-methyl-2H-isothiazol-3-one and 2-methyl-2H-isothiazol-3-
one
Human
and
animal
Not sensitizing
Respiratory Sensitisation
Name
Species
Value
Germ Cell Mutagenicity
Name
Route
Value
Naphtha (petroleum), hydrotreated heavy
In vivo
Not mutagenic
Naphtha (petroleum), hydrotreated heavy
In Vitro
Some positive data exist, but the data are not
sufficient for classification
Ceramic materials and wares, chemicals
In Vitro
Some positive data exist, but the data are not
sufficient for classification
Mixture of 5-chloro-2-methyl-2H-isothiazol-3-one and 2-methyl-2H-isothiazol-3-
one
In vivo
Not mutagenic
Mixture of 5-chloro-2-methyl-2H-isothiazol-3-one and 2-methyl-2H-isothiazol-3-
one
In Vitro
Some positive data exist, but the data are not
sufficient for classification
Carcinogenicity
Name
Route
Species
Value
Naphtha (petroleum), hydrotreated heavy
Dermal
Mouse
Some positive data exist, but the data are not
sufficient for classification
Naphtha (petroleum), hydrotreated heavy
Inhalation
Human
and
animal
Some positive data exist, but the data are not
sufficient for classification
Ceramic materials and wares, chemicals
Inhalation
Multiple
animal
species
Some positive data exist, but the data are not
sufficient for classification
Mixture of 5-chloro-2-methyl-2H-isothiazol-3-one and 2-methyl-
2H-isothiazol-3-one
Dermal
Mouse
Not carcinogenic
Mixture of 5-chloro-2-methyl-2H-isothiazol-3-one and 2-methyl-
2H-isothiazol-3-one
Ingestion
Rat
Not carcinogenic
Reproductive Toxicity
Reproductive and/or Developmental Effects
Name
Route
Value
Species
Test result
Exposure
Duration
Naphtha (petroleum), hydrotreated heavy
Inhalation
Not toxic to development
Rat
NOAEL 2.4
mg/l
during
organogenesis
Mixture of 5-chloro-2-methyl-2H-
isothiazol-3-one and 2-methyl-2H-
isothiazol-3-one
Ingestion
Not toxic to female reproduction
Rat
NOAEL 10
mg/kg/day
2 generation
Mixture of 5-chloro-2-methyl-2H-
isothiazol-3-one and 2-methyl-2H-
Ingestion
Not toxic to male reproduction
Rat
NOAEL 10
mg/kg/day
2 generation