MEGUIAR'S D155 - Manual (Page 7)

D155, Last Touch Detailing Spray (DX-73C): D15501, D15505
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Carcinogenicity
Name Route Species Value
1-propoxypropan-2-ol No data available
Propylene Glycol Dermal Mouse Not carcinogenic
Propylene Glycol Ingestion Multiple animal
species Not carcinogenic
Reproductive Toxicity
Reproductive and/or Developmental Effects
Name Route Value Species Test result Exposure Duration
1-propoxypropan-2-
ol Inhalation Some positive
developmental data
exist, but the data are
not sufficient for
classification Rat NOAEL 3.6
mg/l during organogenesis
Propylene Glycol Ingestion Not toxic to female
reproduction Mouse NOAEL
10,100
mg/kg/day 2 generation
Propylene Glycol Ingestion Not toxic to male
reproduction Mouse NOAEL
10,100
mg/kg/day 2 generation
Propylene Glycol Ingestion Not toxic to
development Multiple animal
species NOAEL
1,230
mg/kg/day during organogenesis
Target Organ(s)
Specific Target Organ Toxicity - single exposure
Name Route Target
Organ(s) Value Species Test result Exposure
Duration
1-
propoxypropa
n-2-ol Inhalation central nervous
system
depression May cause
drowsiness or
dizziness
1-
propoxypropa
n-2-ol Inhalation respiratory
irritation May cause
respiratory
irritation
Propylene
Glycol Ingestion central nervous
system
depression May cause
drowsiness or
dizziness NOAEL N/A
Specific Target Organ Toxicity - repeated exposure
Name Route Target
Organ(s) Value Species Test result Exposure
Duration
1-
propoxypropa
n-2-ol Inhalation liver | kidney
and/or bladder Some positive
data exist, but the
data are not
sufficient for
classification Rat NOAEL 9.5
mg/l 11 days
Propylene
Glycol Ingestion hematopoietic
system Some positive
data exist, but the
data are not
sufficient for
classification Multiple
animal species NOAEL 1,370
mg/kg/day 117 days
Propylene
Glycol Ingestion kidney and/or
bladder All data are
negative Dog NOAEL 5,000
mg/kg/day 104 weeks
Aspiration Hazard