MEGUIAR'S D161 - Manual (Page 8)

D161, Detailer Silicone-Free Dressing (DX-77B): D16101, D16105
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Skin Sensitisation
Name Species Value
Glycerin Guinea
pig Not sensitizing
Propane-1,2-diol Human Some positive data exist, but the data are not
sufficient for classification
Mixture of 5-chloro-2-methyl-2H-isothiazol-3-one and 2-methyl-2H-isothiazol-3-
one Human
and
animal Sensitising
Photosensitisation
Name Species Value
Mixture of 5-chloro-2-methyl-2H-isothiazol-3-one and 2-methyl-2H-isothiazol-3-
one Human
and
animal Not sensitizing
Respiratory Sensitisation
Name Species Value
Germ Cell Mutagenicity
Name Route Value
Propane-1,2-diol In Vitro Not mutagenic
Propane-1,2-diol In vivo Not mutagenic
Mixture of 5-chloro-2-methyl-2H-isothiazol-3-one and 2-methyl-2H-isothiazol-3-
one In vivo Not mutagenic
Mixture of 5-chloro-2-methyl-2H-isothiazol-3-one and 2-methyl-2H-isothiazol-3-
one In Vitro Some positive data exist, but the data are not
sufficient for classification
Carcinogenicity
Name Route Species Value
Glycerin Ingestion Mouse Some positive data exist, but the data are not
sufficient for classification
Propane-1,2-diol Dermal Mouse Not carcinogenic
Propane-1,2-diol Ingestion Multiple
animal
species Not carcinogenic
Mixture of 5-chloro-2-methyl-2H-isothiazol-3-one and 2-methyl-
2H-isothiazol-3-one Dermal Mouse Not carcinogenic
Mixture of 5-chloro-2-methyl-2H-isothiazol-3-one and 2-methyl-
2H-isothiazol-3-one Ingestion Rat Not carcinogenic
Reproductive Toxicity
Reproductive and/or Developmental Effects
Name Route Value Species Test result Exposure
Duration
Glycerin Ingestion Not toxic to female reproduction Rat NOAEL
2,000
mg/kg/day 2 generation
Glycerin Ingestion Not toxic to male reproduction Rat NOAEL
2,000
mg/kg/day 2 generation
Glycerin Ingestion Not toxic to development Rat NOAEL
2,000
mg/kg/day 2 generation
Propane-1,2-diol Ingestion Not toxic to female reproduction Mouse NOAEL
10,100
mg/kg/day 2 generation
Propane-1,2-diol Ingestion Not toxic to male reproduction Mouse NOAEL
10,100
mg/kg/day 2 generation