MEGUIAR'S D185 - Manual (Page 8)

G185, Leather Cleaner (24-01C): G18516
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Reproductive Toxicity
Reproductive and/or Developmental Effects
Name Route Value Species Test result Exposure
Duration
Sodium Metasilicate Ingestion Some positive developmental data exist,
but the data are not sufficient for
classification Mouse NOAEL 200
mg/kg/day during
gestation
Sulphonic acids, C14-16-alkane hydroxy
and C14-16-alkene, sodium salts Ingestion Not toxic to female reproduction Rat NOAEL 871
mg/kg 2 generation
Sulphonic acids, C14-16-alkane hydroxy
and C14-16-alkene, sodium salts Ingestion Not toxic to male reproduction Rat NOAEL 891
mg/kg 2 generation
Sulphonic acids, C14-16-alkane hydroxy
and C14-16-alkene, sodium salts Ingestion Some positive developmental data exist,
but the data are not sufficient for
classification Rabbit NOAEL 600
mg/kg during
organogenesis
Target Organ(s)
Specific Target Organ Toxicity - single exposure
Name Route Target Organ(s) Value Species Test result Exposure
Duration
Sodium Metasilicate Inhalation respiratory irritation May cause respiratory irritation official
classifica
tion NOAEL Not
available
Specific Target Organ Toxicity - repeated exposure
Name Route Target Organ(s) Value Species Test result Exposure
Duration
Sodium Metasilicate Ingestion kidney and/or
bladder Some positive data exist, but the
data are not sufficient for
classification Dog LOAEL
2,400
mg/kg/day 4 weeks
Sodium Metasilicate Ingestion endocrine system Some positive data exist, but the
data are not sufficient for
classification Rat NOAEL 804
mg/kg/day 3 months
Sulphonic acids, C14-16-
alkane hydroxy and C14-
16-alkene, sodium salts Ingestion liver Some positive data exist, but the
data are not sufficient for
classification Rat NOAEL 500
mg/kg/day 6 months
Sulphonic acids, C14-16-
alkane hydroxy and C14-
16-alkene, sodium salts Ingestion kidney and/or
bladder Some positive data exist, but the
data are not sufficient for
classification Rat NOAEL 500
mg/kg 6 months
Sodium Metasilicate Ingestion blood All data are negative Rat NOAEL 804
mg/kg/day 3 months
Sodium Metasilicate Ingestion heart | liver All data are negative Rat NOAEL
1,259
mg/kg/day 8 weeks
Aspiration Hazard
Name Value
Please contact the address or phone number listed on the first page of the SDS for additional toxicological information
on this material and/or its components.
SECTION 12: Ecological information
The information below may not be consistent with the material classification in Section 2 if specific ingredient classifications
are mandated by a competent authority. Additional information leading to material classification in Section 2 is available
upon request. In addition, environmental fate and effects data on ingredients may not be reflected in this section because an
ingredient is present below the threshold for labelling, an ingredient is not expected to be available for exposure, or the data
is considered not relevant to the material as a whole.
12.1. Toxicity